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Why does Wuhan coronavirus genome end in aaaaa.. (33 a's)?

 4 years ago
source link: https://bioinformatics.stackexchange.com/questions/11227/why-does-the-wuhan-coronavirus-genome-end-in-aaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
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The Wuhan coronavirus's genome was released, and is now available on Genbank. Looking at it...

1 attaaaggtt tataccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct
   61 gttctctaaa cgaactttaa aatctgtgtg gctgtcactc ggctgcatgc ttagtgcact
  121 cacgcagtat aattaataac taattactgt cgttgacagg acacgagtaa ctcgtctatc
  ...
29761 acagtgaaca atgctaggga gagctgccta tatggaagag ccctaatgtg taaaattaat
29821 tttagtagtg ctatccccat gtgattttaa tagcttctta ggagaatgac aaaaaaaaaa
29881 aaaaaaaaaa aaaaaaaaaa aaa

Wuhan seafood market pneumonia virus isolate Wuhan-Hu-1, complete genome , Genbank

Geeze, that's a lot of a nucleotides---I don't think that's just random. I would guess that it's either an artifact of the sequencing process, or there is some underlying biological reason.

Question: Why does the Wuhan coronavirus genome end in 33 a's?


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